Description

2-Chloro-2-(4'-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenylhydrazono)Acetic Acid Ethyl Ester is a specialized organic compound that serves as a valuable synthetic intermediate. Its molecular architecture, featuring both a boronic ester pinacol group and a reactive hydrazono-acetate moiety, makes it a versatile building block for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, cross-coupling reactions, and the synthesis of novel heterocycles.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring boronic acid/ester functionality for Suzuki-Miyaura cross-coupling reactions.
• Medicinal Chemistry Research: Used in the discovery and optimization of new drug candidates, enabling the rapid assembly of diverse chemical libraries for biological screening.
• Agrochemical Synthesis: Serves as a building block for developing novel pesticides, herbicides, and fungicides with potentially enhanced efficacy.
• Material Science: Potential use in the synthesis of organic electronic materials, ligands for catalysts, and advanced polymers.
• Chemical Biology Probes: Can be utilized to create labeled compounds or probes for studying biological processes and target engagement.

Basic Information

Product Name	2-Chloro-2-(4'-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenylhydrazono)Acetic Acid Ethyl Ester
CAS No.	1310384-14-5
Molecular Formula	C₁₆H₂₂BClN₂O₄
Molecular Weight	352.62 g/mol
Synonyms	Ethyl 2-chloro-2-[2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]hydrazinylidene]acetate; 2-Chloro-2-(2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)hydrazono)ethyl acetate; (4-(2-(1-Chloro-2-ethoxy-2-oxoethylidene)hydrazinyl)phenyl)boronic acid pinacol ester; CAS 1310384-14-5
EINECS	Contact for details

Quality Control

Our production of 2-Chloro-2-(4'-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenylhydrazono)Acetic Acid Ethyl Ester adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your critical research and development work. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.