Description

Pyrazole-3-Boronic Acid Hydrate is a versatile and high-purity boronic acid derivative essential for modern synthetic chemistry. Its primary value lies in its crucial role as a key building block in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is critically needed by research and development teams in the pharmaceutical, agrochemical, and material science industries for drug discovery, catalyst development, and advanced polymer synthesis.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing pyrazole and biaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific heterocyclic architectures.
• Material Science & OLED Development: Serves as a precursor for creating advanced organic electronic materials, including ligands for metal-organic frameworks (MOFs) and emissive layers in OLED devices.
• Catalyst & Ligand Preparation: Employed in the synthesis of specialized ligands for transition metal catalysts used in asymmetric synthesis and other catalytic processes.
• Chemical Biology & Bioconjugation: Utilized in the development of chemical probes and bioconjugation reagents due to its selective reactivity with diols and other functional groups.
• Academic & Contract Research: A fundamental reagent for methodological development and complex molecule synthesis in academic laboratories and CROs (Contract Research Organizations).

Basic Information

Product Name	Pyrazole-3-Boronic Acid Hydrate
CAS No.	1310383-92-6
Molecular Formula	C3H7BN2O3
Molecular Weight	129.91 g/mol (Anhydrous basis)
Synonyms	3-Pyrazoleboronic Acid Hydrate; 1H-Pyrazole-3-boronic Acid Hydrate; (1H-Pyrazol-3-yl)boronic Acid Hydrate; Pyrazol-3-ylboronic Acid Hydrate; 3-Boronopyrazole Hydrate; 3-Pyrazolylboronic Acid Hydrate; Pyrazole-3-yl-B(OH)2 Hydrate
EINECS	Contact for details

Quality Control

Every batch of Pyrazole-3-Boronic Acid Hydrate is manufactured and tested under strict quality management systems to ensure consistency and reliability for your critical applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (by HPLC/NMR), water content (KF), and residual solvent levels. Our quality commitment aligns with the standards expected in cGMP and ISO environments for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) for long-term storage to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤5.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.