Description

6-Methyl-1H-Indazol-4-Yl-4-Boronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing novel active pharmaceutical ingredients (APIs) and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, especially those containing indazole or complex heterocyclic scaffolds.
• Suzuki-Miyaura Cross-Coupling Reagent: Used for the formation of carbon-carbon bonds to create novel biaryl compounds in medicinal chemistry research.
• Agrochemical Development: Serves as a building block for creating new herbicides, fungicides, and insecticides with improved efficacy.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs or molecular sensors.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	6-Methyl-1H-Indazol-4-Yl-4-Boronic Acid
CAS No.	1310383-73-3
Molecular Formula	C9H9BN2O2
Molecular Weight	188.00 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-methyl-1H-indazole; 6-Methyl-1H-indazole-4-boronic acid; 6-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole; 6-Methyl-1H-indazol-4-ylboronic acid; (6-Methyl-1H-indazol-4-yl)boronic acid; B-(6-Methyl-1H-indazol-4-yl)boronic acid; 1310383-73-3
EINECS	Contact for details

Quality Control

Every batch of 6-Methyl-1H-Indazol-4-Yl-4-Boronic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive coupling reactions and pharmaceutical R&D. A Certificate of Analysis (COA) detailing purity (typically >95% by HPLC), identity confirmation (by 1H NMR and IR), and impurity profile is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) for long-term storage and when dispensing to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.