Description

3-Methyl-1H-Indazole-4-Boronic Acid is a high-purity boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation, a fundamental step in constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients through Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those containing the indazole heterocycle, for therapeutic areas such as oncology and CNS disorders.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its ability to introduce the 3-methylindazole moiety into complex molecules.
• Material Science Research: Employed in the creation of advanced organic materials, including organic light-emitting diodes (OLEDs) and conductive polymers, where precise molecular structure is paramount.
• Chemical Biology Probes: Serves as a versatile handle for bioconjugation and the development of chemical probes to study biological processes and protein function.
• Catalyst Ligand Precursor: Can be utilized to synthesize novel ligands for transition metal catalysts used in asymmetric synthesis and other specialized chemical transformations.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	3-Methyl-1H-Indazole-4-Boronic Acid
CAS No.	1310383-41-5
Molecular Formula	C8H9BN2O2
Molecular Weight	175.98 g/mol
Synonyms	3-Methyl-1H-indazol-4-ylboronic acid; (3-Methyl-1H-indazol-4-yl)boronic acid; 4-Borono-3-methyl-1H-indazole; 3-Methyl-4-indazoleboronic acid; 3-Methyl-1H-indazole-4-boronic acid pinacol ester (protected form); 3-Me-1H-Indazole-4-BA; B-(3-Methyl-1H-indazol-4-yl)boronic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Methyl-1H-Indazole-4-Boronic Acid is manufactured under strict quality management protocols. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive cross-coupling reactions. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (by HPLC/NMR), identity confirmation, and residual solvent levels. Our quality systems are designed to support cGMP and ISO standards for traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. For long-term storage, consider storing desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.