Description

3-(Methoxycarbonyl)Thiophene-2-Boronic Acid is a high-value organoboron building block, specifically a thiophene-based boronic acid ester, essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for synthesizing novel active ingredients and functional heterocycles.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those containing functionalized thiophene cores.
• Agrochemical Synthesis: Used in creating advanced active ingredients for crop protection products.
• Material Science Research: Employed in the development of organic electronic materials, such as polymers and small molecules for OLEDs or organic photovoltaics.
• Chemical Biology & Probe Development: Serves as a versatile handle for bioconjugation and the creation of molecular probes.
• Academic & Contract Research: Fundamental reagent for methodological development and custom synthesis in research laboratories.
• Scale-up Process Chemistry: Suitable for optimization and pilot-scale production of target molecules in fine chemical manufacturing.

Basic Information

Product Name	3-(Methoxycarbonyl)Thiophene-2-Boronic Acid
CAS No.	1310383-30-2
Molecular Formula	C7H9BO4S
Molecular Weight	199.98 g/mol
Synonyms	2-Borono-3-methoxycarbonylthiophene; Methyl 2-boronothiophene-3-carboxylate; 3-Carbomethoxythiophene-2-boronic Acid; (3-Methoxycarbonylthiophen-2-yl)boronic Acid; Thiophene-2-boronic acid, 3-(methoxycarbonyl)-; 1310383-30-2; Methyl 3-thiophenecarboxylate-2-boronic acid
EINECS	Contact for details

Quality Control

Our 3-(Methoxycarbonyl)Thiophene-2-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive cross-coupling applications. Comprehensive Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0% (as C7H9BO4S)
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.