Description

6-(iso-Propoxy)Pyridine-2-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its enhanced stability compared to the free boronic acid, making it an essential reagent for reliable and efficient cross-coupling reactions. This compound is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for the formation of carbon-carbon bonds between aryl/heteroaryl halides and organoboron compounds, fundamental in drug discovery and material science.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing functionalized pyridine scaffolds.
• Agrochemical Development: Serves as a building block for creating novel herbicides, fungicides, and insecticides with specific activity profiles.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Used in the development of organic electronic materials, such as those for OLEDs and semiconductors.
• Chemical Biology & Probe Development: Utilized in the creation of molecular probes and bioconjugates for studying biological systems.

Basic Information

Product Name	6-(iso-Propoxy)Pyridine-2-Boronic Acid Pinacol Ester
CAS No.	1310383-08-4
Molecular Formula	C14H22BNO3
Molecular Weight	263.14 g/mol
Synonyms	2-(6-Isopropoxypyridin-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 6-Isopropoxy-2-pyridineboronic acid pinacol ester; 6-(Isopropoxy)-2-pyridinylboronic acid pinacol ester; 2-(6-(Propan-2-yloxy)pyridin-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol 6-isopropoxypyridine-2-boronate; Boronic acid, B-[6-(1-methylethoxy)-2-pyridinyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 6-(iso-Propoxy)Pyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.