Description

3-Fluoro-6-Methylpyridine-2-Boronic Acid Pinacol Ester is a high-value, organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for constructing fluorinated pyridine cores in active pharmaceutical ingredients (APIs), leveraging the Suzuki reaction for efficient library synthesis and lead optimization.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the fluorinated pyridine moiety enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized bidentate or monodentate ligands used in homogeneous catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology & Probe Design: Useful for incorporating fluorinated pyridine tags into biomolecules or for creating chemical probes to study biological systems.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) serving clients in life sciences.

Basic Information

Product Name	3-Fluoro-6-Methylpyridine-2-Boronic Acid Pinacol Ester
CAS No.	1310383-07-3
Molecular Formula	C₁₂H₁₇BFNO₂
Molecular Weight	237.08 g/mol
Synonyms	2-(3-Fluoro-6-methylpyridin-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (3-Fluoro-6-methylpyridin-2-yl)boronic acid pinacol ester; 3-Fluoro-6-methylpyridine-2-boronic acid pinacol ester; 3-Fluoro-6-methyl-2-pyridineboronic acid pinacol ester; 2-(3-Fluoro-6-methyl-2-pyridinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Fluoro-6-methylpyridine-2-ylboronic acid pinacol ester; Boronic acid, B-(3-fluoro-6-methyl-2-pyridinyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our production of 3-Fluoro-6-Methylpyridine-2-Boronic Acid Pinacol Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical synthetic applications. Each lot is characterized by advanced analytical techniques including NMR (¹H, ¹³C, ¹⁹F, ¹¹B), HPLC, and GC to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.