Description

6-(4-Methylpiperazin-1-Yl)Pyridine-2-Boronic Acid Pinacol Ester is a high-value, organoboron building block crucial for modern synthetic chemistry. This compound matters for its role as a key intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily needed by pharmaceutical, agrochemical, and advanced materials research and development teams for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Research: Used in the development of new active ingredients for crop protection, leveraging its boronic ester functionality for efficient carbon-carbon bond formation.
• Material Science: Serves as a building block for creating organic electronic materials, such as ligands for OLEDs or conductive polymers, where the pyridine and piperazine motifs offer tunable electronic properties.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and bioconjugates for studying biological pathways and protein interactions.
• Catalyst Ligand Synthesis: Used to construct sophisticated nitrogen-containing ligands for transition metal catalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	6-(4-Methylpiperazin-1-Yl)Pyridine-2-Boronic Acid Pinacol Ester
CAS No.	1310383-04-0
Molecular Formula	C16H26BN3O2
Molecular Weight	303.21 g/mol
Synonyms	6-(4-Methyl-1-piperazinyl)-2-pyridineboronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(4-methylpiperazin-1-yl)pyridine; 6-(4-Methylpiperazin-1-yl)pyridine-2-boronic acid pinacol ester; 6-(N-Methylpiperazino)pyridine-2-boronic acid pinacol ester; 2-Borono-6-(4-methyl-1-piperazinyl)pyridine pinacol ester; (6-(4-Methylpiperazin-1-yl)pyridin-2-yl)boronic acid pinacol ester; B-[6-(4-Methyl-1-piperazinyl)-2-pyridinyl]boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 6-(4-Methylpiperazin-1-Yl)Pyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support development projects requiring material suitable for use under cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.