Description

2-tert-Butyloxycarbonylamino-6-Methylpyridine-3-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid ester building block essential for modern synthetic chemistry. This compound is specifically designed for use in Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. It is a critical intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in medicinal chemistry programs.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile organoboron reagent for the formation of carbon-carbon bonds, enabling the construction of complex biaryl and heterobiaryl structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific pyridine-based scaffolds.
• Material Science Research: Potential precursor for the development of organic electronic materials, ligands for catalysts, and advanced polymers.
• Chemical Biology & Proteomics: Can be utilized in the synthesis of molecular probes and tools for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-tert-Butyloxycarbonylamino-6-Methylpyridine-3-Boronic Acid Pinacol Ester
CAS No.	1309982-66-8
Molecular Formula	C₁₇H₂₇BN₂O₄
Molecular Weight	334.22 g/mol
Synonyms	2-((tert-Butoxycarbonyl)amino)-6-methylpyridine-3-boronic acid pinacol ester; 2-(Boc-amino)-6-methyl-3-pyridineboronic acid pinacol ester; 2-(N-Boc-amino)-6-methylpyridin-3-ylboronic acid pinacol ester; 6-Methyl-2-((tert-butoxycarbonyl)amino)pyridine-3-boronic acid pinacol ester; Boc-6-methyl-2-aminopyridin-3-yl-Bpin; 1309982-66-8; (2-((tert-Butoxycarbonyl)amino)-6-methylpyridin-3-yl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-tert-Butyloxycarbonylamino-6-Methylpyridine-3-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive coupling reactions. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light). For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.