Description

4-(Methoxycarbonyl)-6-Methylpyridine-2-Boronic Acid Pinacol Ester is a high-purity, synthetically valuable boronic ester derivative. This compound matters as a key protected boronic acid building block, offering enhanced stability and solubility for advanced cross-coupling reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex heterocyclic molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a critical reagent for constructing biaryl and heterobiaryl systems in medicinal chemistry.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing functionalized pyridine cores.
• Agrochemical Synthesis: Employed in creating novel herbicides, fungicides, and insecticides with tailored properties.
• Material Science Research: Acts as a precursor for organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the development of molecular probes and diagnostic agents due to its reactive boronate functionality.
• Process Chemistry & Scale-up: The pinacol ester group provides improved handling characteristics for large-scale manufacturing processes.

Basic Information

Product Name	4-(Methoxycarbonyl)-6-Methylpyridine-2-Boronic Acid Pinacol Ester
CAS No.	1309982-35-1
Molecular Formula	C14H20BNO4
Molecular Weight	277.12 g/mol
Synonyms	6-Methyl-4-(methoxycarbonyl)pyridine-2-boronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-methylisonicotinic acid methyl ester; Methyl 6-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2-carboxylate; 4-Carbomethoxy-6-methyl-2-pyridineboronic acid pinacol ester; Pinacol [4-(methoxycarbonyl)-6-methyl-2-pyridyl]boronate
EINECS	Contact for details

Quality Control

Our 4-(Methoxycarbonyl)-6-Methylpyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Products undergo rigorous analytical testing, including NMR, HPLC, and GC-MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with research and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.