Description

6-(n-Propoxy)Pyridine-2-Boronic Acid Pinacol Ester is a high-purity organoboron building block, specifically a protected boronic acid ester, critical for modern synthetic chemistry. Its primary value lies in enabling efficient, selective cross-coupling reactions, such as the Suzuki-Miyaura reaction, which is foundational for constructing complex molecules in pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists working in pharmaceutical intermediates, advanced material science, and ligand synthesis. The pinacol ester group provides enhanced stability, making it a reliable and convenient reagent for demanding synthetic applications.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for constructing pyridine-containing active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require specific pyridine-based architectures.
• Material Science & OLED Development: Serves as a precursor for creating organic semiconductors, electron-transport materials, and light-emitting layers in electronic devices.
• Ligand & Catalyst Design: Employed in the synthesis of novel bidentate or polydentate ligands for transition metal catalysis.
• Chemical Biology & Probe Development: Useful for creating molecular probes and bioconjugates where a stable boronic ester handle is required for further functionalization.
• Academic & Contract Research: A valuable reagent for methodology development and complex molecule synthesis in academic and industrial R&D laboratories.

Basic Information

Product Name	6-(n-Propoxy)Pyridine-2-Boronic Acid Pinacol Ester
CAS No.	1309982-31-7
Molecular Formula	C₁₄H₂₂BNO₃
Molecular Weight	263.14 g/mol
Synonyms	6-Propoxypyridine-2-boronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-propoxypyridine; 6-Propoxy-2-pyridineboronic acid pinacol ester; 2-(6-Propoxypyridin-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 6-n-Propoxypyridine-2-boronic acid pinacol ester; 6-Propoxy-2-pyridinylboronic acid pinacol ester; Boronic acid, B-(6-propoxy-2-pyridinyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 6-(n-Propoxy)Pyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced techniques including NMR, HPLC, and GC to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to a quality management system and can supply material compliant with relevant standards for advanced intermediate use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.