Description

6-(n-Propoxy)Pyridine-2-Boronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in its role as a key reagent in cross-coupling reactions, enabling the efficient construction of complex molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and fine chemical synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A fundamental reagent for forming carbon-carbon bonds between aryl/heteroaryl halides and boronic acids, essential for constructing biaryl structures in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate Synthesis: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, particularly those containing functionalized pyridine scaffolds.
• Agrochemical Research & Development: Used in creating new active ingredients for crop protection products, leveraging its ability to introduce the propoxy-pyridine moiety into target molecules.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for metal catalysts or as a component in metal-organic frameworks (MOFs) and functional materials.
• Chemical Biology & Probe Synthesis: Utilized for labeling and modifying biomolecules or creating molecular probes for diagnostic and research applications.
• Process Chemistry & Scale-up: Provides a reliable, high-quality starting material for optimizing and scaling up synthetic routes from laboratory to pilot plant and commercial production.

Basic Information

Product Name	6-(n-Propoxy)Pyridine-2-Boronic Acid
CAS No.	1309982-30-6
Molecular Formula	C8H12BNO3
Molecular Weight	181.00 g/mol
Synonyms	6-Propoxypyridine-2-boronic Acid; 2-Borono-6-propoxy-pyridine; (6-Propoxypyridin-2-yl)boronic Acid; 6-n-Propoxypyridine-2-boronic Acid; 6-Propoxy-2-pyridineboronic Acid; 2-(6-Propoxypyridinyl)boronic Acid; Boronic acid, B-(6-propoxy-2-pyridinyl)-; 1309982-30-6
EINECS	Contact for details

Quality Control

Our 6-(n-Propoxy)Pyridine-2-Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive cross-coupling chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and oxidizable nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after opening the primary container.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.