Description

6-(Cyclopropylamino)Pyridine-2-Boronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a substituted pyridine scaffold, enabling the construction of complex nitrogen-containing heterocycles. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand for Catalysis: Serves as a starting material for synthesizing sophisticated ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, due to its conjugated pyridine-boronic acid structure.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and sensors for studying biological processes.
• Library Synthesis for Drug Discovery: A valuable building block for parallel and combinatorial chemistry to generate diverse compound libraries for high-throughput screening.

Basic Information

Product Name	6-(Cyclopropylamino)Pyridine-2-Boronic Acid
CAS No.	1309982-29-3
Molecular Formula	C8H11BN2O2
Molecular Weight	178.00 g/mol
Synonyms	2-Borono-6-(cyclopropylamino)pyridine; 6-Cyclopropylaminopyridine-2-boronic Acid; (6-(Cyclopropylamino)pyridin-2-yl)boronic Acid; 2-Pyridineboronic acid, 6-(cyclopropylamino)-; B-[6-(Cyclopropylamino)-2-pyridinyl]boronic Acid; 1309982-29-3; 6-Cyclopropylaminopyridine-2-boronic acid pinacol ester (common protected form)
EINECS	Contact for details

Quality Control

Our 6-(Cyclopropylamino)Pyridine-2-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for advanced research and process chemistry. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.