Description

6-Bromo-4-Methylpyridine-3-Boronic Acid Pinacol Ester is a high-value, organoboron building block essential for modern synthetic chemistry. This compound matters as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used to construct novel heterocyclic scaffolds for new-generation herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for target identification and validation in drug discovery.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and complex intermediates under cGMP conditions.

Basic Information

Item	Detail
Product Name	6-Bromo-4-Methylpyridine-3-Boronic Acid Pinacol Ester
CAS No.	1309982-23-7
Molecular Formula	C₁₂H₁₇BBrNO₂
Molecular Weight	298.99 g/mol
Synonyms	6-Bromo-4-methylpyridine-3-boronic acid pinacol ester; (6-Bromo-4-methylpyridin-3-yl)boronic acid pinacol ester; 3-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-picoline; 6-Bromo-4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 6-Bromo-4-methylpyridine-3-boronic acid, pinacol ester; Boronic acid, B-(6-bromo-4-methyl-3-pyridinyl)-, 1,1-dimethylethyl ester; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 6-Bromo-4-Methylpyridine-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to supply chain reliability and traceability ensures you receive a product that meets your exact research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and easily oxidized. Allow the sealed container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.