Description

(6-Aminopyridin-3-Yl)Boronic Acid Hydrochloride is a high-purity, pharmaceutically relevant boronic acid derivative. This compound is a critical building block in modern medicinal chemistry, primarily serving as a key intermediate in the synthesis of complex molecules via Suzuki-Miyaura cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for targeted cancer therapies and kinase inhibitors.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for constructing biaryl and heterobiaryl structures central to many drug candidates.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Potential building block for creating advanced organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Employed in the design of molecular probes and activity-based protein profiling (ABPP) reagents.
• Library Synthesis for Drug Discovery: Enables the rapid generation of diverse compound libraries for high-throughput screening (HTS) campaigns.

Basic Information

Product Name	(6-Aminopyridin-3-Yl)Boronic Acid Hydrochloride
CAS No.	1309982-15-7
Molecular Formula	C5H8BClN2O2
Molecular Weight	174.39 g/mol
Synonyms	5-(Aminomethyl)-2-pyridineboronic acid hydrochloride; (6-Amino-3-pyridinyl)boronic acid hydrochloride; 2-Amino-5-boronopyridinium chloride; 3-Amino-6-pyridylboronic acid HCl; 5-(Aminomethyl)pyridine-2-boronic acid hydrochloride; 2-Pyridineboronic acid, 5-(aminomethyl)-, hydrochloride; 6-Amino-3-pyridylboronic acid hydrochloride
EINECS	Contact for details

Quality Control

Our (6-Aminopyridin-3-Yl)Boronic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance as a synthetic building block. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and must be handled in a dry environment to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.