Description

Diethyl 5-(4,4,5,5-Tetramethyl-1,3,2- Dioxaborolan-2-Yl)-1,3-Benzene-Dicarboxylate is a high-purity, synthetically valuable aromatic boronic ester derivative. This compound serves as a critical advanced pharmaceutical intermediate and versatile building block in modern organic synthesis, enabling the formation of complex carbon-carbon bonds. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for palladium-catalyzed coupling to introduce functionalized aromatic rings into target molecules.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) for various therapeutic areas.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and insecticides.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and conductive polymers.
• Ligand and Catalyst Development: Useful for synthesizing novel ligands and organometallic catalysts.
• Chemical Biology Probes: Facilitates the labeling and modification of biomolecules for research purposes.

Basic Information

Item	Details
Product Name	Diethyl 5-(4,4,5,5-Tetramethyl-1,3,2- Dioxaborolan-2-Yl)-1,3-Benzene-Dicarboxylate
CAS No.	1309982-02-2
Molecular Formula	C20H29BO6
Molecular Weight	376.26 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isophthalic Acid Diethyl Ester; Diethyl 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isophthalate; 1,3-Benzenedicarboxylic Acid, 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-, Diethyl Ester; Diethyl 5-(Pinacolatoboryl)isophthalate; 5-(Pinacolatoboryl)isophthalic Acid Diethyl Ester
EINECS	Contact for details

Quality Control

Our Diethyl 5-(4,4,5,5-Tetramethyl-1,3,2- Dioxaborolan-2-Yl)-1,3-Benzene-Dicarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.