Description

6-(Cyclopropylamino)Pyridine-2-Boronic Acid Pinacol Ester is a high-value, organoboron building block crucial for modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, specifically Suzuki-Miyaura couplings, to construct complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing pyridine and cyclopropyl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific heterocyclic structures.
• Material Science: Serves as a precursor for creating functionalized polymers, ligands for catalysts, and organic electronic materials.
• Suzuki-Miyaura Cross-Coupling: The pinacol ester protects the boronic acid, enhancing stability and handling for precise C-C bond formation in complex molecule assembly.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries.
• Ligand Synthesis: Used to prepare specialized bidentate or tridentate ligands for transition metal catalysis.

Basic Information

Product Name	6-(Cyclopropylamino)Pyridine-2-Boronic Acid Pinacol Ester
CAS No.	1309981-36-9
Molecular Formula	C14H21BN2O2
Molecular Weight	260.15 g/mol
Synonyms	6-(Cyclopropylamino)-2-pyridineboronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(cyclopropylamino)pyridine; 6-Cyclopropylamino-2-pyridinylboronic acid pinacol ester; (6-(Cyclopropylamino)pyridin-2-yl)boronic acid pinacol ester; B-[6-(Cyclopropylamino)-2-pyridinyl]boronic acid pinacol ester; 1309981-36-9; Pinacol 6-(cyclopropylamino)pyridine-2-boronate
EINECS	Contact for details

Quality Control

Our 6-(Cyclopropylamino)Pyridine-2-Boronic Acid Pinacol Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring traceability and consistency, from early-stage research to scale-up development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C (refrigerated) or -20°C for extended periods.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.