Description

3-Cyanopyridine-2-Boronic Acid Pinacol Ester is a high-value, multi-functional organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in pharmaceutical and agrochemical research. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing pyridine and cyanopyridine motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific heterocyclic structures.
• Material Science Research: Serves as a precursor for creating organic electronic materials, ligands for catalysis, and functional polymers.
• Suzuki-Miyaura Cross-Coupling: The primary application is as a versatile boronic ester reagent for palladium-catalyzed coupling with aryl/heteroaryl halides.
• Chemical Library Development: Enables the rapid, parallel synthesis of diverse compound libraries for high-throughput screening in drug discovery.
• Ligand and Catalyst Design: Used to construct complex, bidentate, or polydentate ligands for transition metal catalysis.

Basic Information

Item	Details
Product Name	3-Cyanopyridine-2-Boronic Acid Pinacol Ester
CAS No.	1309981-31-4
Molecular Formula	C₁₃H₁₅BN₂O₂
Molecular Weight	242.08 g/mol
Synonyms	2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cyanopyridine; 3-Cyano-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-Cyanopyridine-2-boronic acid pinacol ester; 3-Cyano-2-pyridineboronic acid pinacol ester; Pinacol 3-cyano-2-pyridylboronate; (3-Cyanopyridin-2-yl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 3-Cyanopyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.