Description

5-Methylpyrazine-2-Boronic Acid is a high-purity boronic acid derivative, a key building block in modern synthetic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone methodology for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, catalyst development, and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in heterocyclic chemistry.
• Agrochemical Synthesis: Used in the research and production of novel pesticides, herbicides, and fungicides that require specific pyrazine-based structures.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid reagent for palladium-catalyzed cross-coupling reactions to create biaryl and other complex organic frameworks.
• Material Science Research: Employed in the development of organic electronic materials, ligands for catalysts, and novel polymers.
• Chemical Biology & Proteomics: Can be utilized in the synthesis of molecular probes and inhibitors for studying biological processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke chemical synthesis projects.

Basic Information

Product Name	5-Methylpyrazine-2-Boronic Acid
CAS No.	1309981-12-1
Molecular Formula	C5H7BN2O2
Molecular Weight	137.94 g/mol
Synonyms	(5-Methylpyrazin-2-yl)boronic acid; 2-Borono-5-methylpyrazine; 5-Methyl-2-pyrazineboronic acid; 5-Methylpyrazine-2-boronic acid pinacol ester (common precursor); 1309981-12-1; 5-Methyl-2-pyrazinylboronic acid
EINECS	Contact for details

Quality Control

Our 5-Methylpyrazine-2-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.