Description

5-([tert-Butoxycarbonylamino]Methyl)Pyridine-3-Boronic Acid is a high-purity, advanced pharmaceutical intermediate featuring a protected amine and a boronic acid functional group. This compound is essential for modern synthetic chemistry, particularly in the construction of complex molecules via Suzuki-Miyaura cross-coupling reactions. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those containing pyridine and biaryl motifs.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for creating carbon-carbon bonds with aryl/heteroaryl halides.
• Peptidomimetic Research: Used in the design and synthesis of peptide analogs and protease inhibitors due to its Boc-protected aminomethyl side chain.
• Agrochemical Synthesis: Employed in the research and development of new herbicides, fungicides, and insecticides.
• Material Science: Potential precursor for creating functionalized polymers or ligands for catalysts.
• Chemical Biology Probes: Useful for labeling and studying biological systems where a stable, protected amine handle is required.

Basic Information

Product Name	5-([tert-Butoxycarbonylamino]Methyl)Pyridine-3-Boronic Acid
CAS No.	1309981-05-2
Molecular Formula	C12H19BN2O4
Molecular Weight	266.11 g/mol
Synonyms	3-Pyridineboronic acid, 5-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-; 5-((tert-Butoxycarbonylamino)methyl)pyridin-3-ylboronic acid; 5-(Boc-aminomethyl)pyridine-3-boronic acid; Boc-NH-CH2-3-PyridineB(OH)2; N-Boc-3-(5-boronic acid)pyridinemethylamine; tert-Butyl (5-(boronic acid)-3-pyridylmethyl)carbamate; 1309981-05-2
EINECS	Contact for details

Quality Control

Our 5-([tert-Butoxycarbonylamino]Methyl)Pyridine-3-Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.