Description

2-Methyl-4-Trifluoromethoxyphenylboronic Acid, Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. This compound matters for its role as a key intermediate in cross-coupling reactions, enabling the efficient construction of complex molecules. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for drug discovery and advanced material synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for forming carbon-carbon bonds in the synthesis of complex organic molecules.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing trifluoromethoxy-substituted aromatic systems.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with enhanced properties.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors.
• Ligand and Catalyst Development: Useful for synthesizing novel ligands and organometallic catalysts.
• Chemical Biology Probes: Facilitates the creation of labeled compounds and probes for biochemical and medicinal research.

Basic Information

Product Name	2-Methyl-4-Trifluoromethoxyphenylboronic Acid, Pinacol Ester
CAS No.	1309980-29-7
Molecular Formula	C₁₄H₁₈BF₃O₃
Molecular Weight	302.10 g/mol
Synonyms	2-Methyl-4-(trifluoromethoxy)benzeneboronic acid pinacol ester; 2-Methyl-4-(trifluoromethoxy)phenylboronic acid pinacol ester; 4,4,5,5-Tetramethyl-2-[2-methyl-4-(trifluoromethoxy)phenyl]-1,3,2-dioxaborolane; 2-Methyl-4-trifluoromethoxyphenylboronic acid pinacol ester; Boronic acid, B-[2-methyl-4-(trifluoromethoxy)phenyl]-, 1,1-dimethylethyl ester; (2-Methyl-4-(trifluoromethoxy)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Methyl-4-Trifluoromethoxyphenylboronic Acid, Pinacol Ester is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques like NMR and HPLC to confirm identity and assay. Certificates of Analysis (COA) documenting purity and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.