Description

Benzamide, n-[3-Nitro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]- is a high-value, multi-functional chemical intermediate featuring a strategically positioned boronic ester pinacol group. This compound matters because it serves as a critical building block in modern synthetic chemistry, enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions. Pharmaceutical, agrochemical, and advanced materials researchers need this product for the efficient synthesis of complex molecules, including active pharmaceutical ingredients (APIs), liquid crystal materials, and organic electronic compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used to construct complex heterocyclic structures found in modern pesticides and herbicides.
• Material Science: Building block for organic light-emitting diodes (OLEDs), liquid crystals, and other functional organic materials.
• Chemical Research & Development: Essential reagent for medicinal chemistry, process chemistry, and method development in academic and industrial labs.
• Suzuki-Miyaura Cross-Coupling: The boronic ester functionality makes it an ideal partner for palladium-catalyzed coupling with aryl/vinyl halides.
• Complex Molecule Construction: Enables the late-stage functionalization and diversification of molecular scaffolds in a controlled manner.

Basic Information

Product Name	Benzamide, n-[3-Nitro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-
CAS No.	1309980-15-1
Molecular Formula	C19H21BN2O5
Molecular Weight	368.19 g/mol
Synonyms	3-Nitro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N-phenylbenzamide; N-[3-Nitro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]benzamide; 3-Nitro-5-(pinacolboryl)-N-phenylbenzamide; Benzamide, N-[3-nitro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; PINACOL (3-NITRO-5-BENZAMIDOPHENYL)BORONATE; (3-(Benzoylamino)-5-nitrophenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our production of Benzamide, n-[3-Nitro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive applications like pharmaceutical R&D. Each lot undergoes comprehensive analytical characterization including HPLC, NMR, and MS to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.