Description

2,5-Dimethylpyridine-3-Boronic Acid Pinacol Ester is a high-value, organoboron building block crucial for modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone method for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), especially in creating novel heterocyclic compounds with potential therapeutic activity.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific pyridine-based structures.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The quintessential reagent for Suzuki-Miyaura cross-couplings, facilitating carbon-carbon bond formation between aryl/heteroaryl halides and this boronic ester.
• Ligand and Catalyst Development: Utilized to create novel bidentate or tridentate ligands for transition metal catalysis.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological systems and drug-target interactions.

Basic Information

Product Name	2,5-Dimethylpyridine-3-Boronic Acid Pinacol Ester
CAS No.	1309980-12-8
Molecular Formula	C13H20BNO2
Molecular Weight	233.12 g/mol
Synonyms	(3,5-Dimethylpyridin-2-yl)boronic acid pinacol ester; 2,5-Dimethyl-3-pyridineboronic acid pinacol ester; 3,5-Dimethyl-2-pyridineboronic acid pinacol ester; Pinacol (3,5-dimethylpyridin-2-yl)boronate; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,5-dimethylpyridine; 2,5-Dimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Boronic acid, B-(3,5-dimethyl-2-pyridinyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Every batch of 2,5-Dimethylpyridine-3-Boronic Acid Pinacol Ester is produced and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency, critical for sensitive cross-coupling applications. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to verify identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Recommended storage temperature is 2-8°C for extended periods, though short-term storage at 15-25°C is acceptable.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.