Description

2-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Propan-2-Ol is a high-value boronic ester derivative, serving as a critical synthetic intermediate in modern organic chemistry. Its core value proposition lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where precise carbon-carbon bond formation is required for developing active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing sterically hindered biaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific aromatic frameworks.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for OLEDs and components for organic semiconductors.
• Chemical Biology & Probe Development: Employed in the creation of molecular probes and tags for studying biological processes due to its robust coupling chemistry.
• Academic & Process R&D: A valuable reagent for methodology development and scaling up synthetic routes in both academic and industrial research laboratories.

Basic Information

Item	Details
Product Name	2-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Propan-2-Ol
CAS No.	1309980-11-7
Molecular Formula	C15H23BO3
Molecular Weight	262.15 g/mol
Synonyms	2-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-2-ol; 3-(2-Hydroxypropan-2-yl)phenylboronic acid pinacol ester; 2-Methyl-2-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propan-2-ol; 3-(1-Hydroxy-1-methylethyl)benzeneboronic acid pinacol ester; 2-(3-Boronophenyl)propan-2-ol pinacol ester; 1309980-11-7; Pinacol [3-(2-hydroxypropan-2-yl)phenyl]boronate
EINECS	Contact for details

Quality Control

Our production of 2-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Propan-2-Ol adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive coupling reactions. All materials undergo rigorous analytical testing, including HPLC, NMR (¹H and ¹³C), and GC/MS, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and specific impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C to mitigate risks associated with its hygroscopic and easily oxidized nature. Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.