Description

5-Methoxypyridine-2-Boronic Acid Pinacol Ester is a high-purity boronic ester derivative, a crucial protected form of a pyridine-containing boronic acid. This compound serves as a versatile and stable synthetic intermediate in modern cross-coupling chemistry, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those containing functionalized bipyridine or arylpyridine scaffolds.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific heterocyclic structures for bioactivity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs or conductive polymers, where the methoxypyridine unit modifies electronic properties.
• Chemical Biology & Probe Development: Useful for creating molecular probes and bioconjugates due to the reactivity of the boronic ester group under physiological conditions.

Basic Information

Product Name	5-Methoxypyridine-2-Boronic Acid Pinacol Ester
CAS No.	1309601-77-1
Molecular Formula	C₁₂H₁₈BNO₃
Molecular Weight	235.09 g/mol
Synonyms	5-Methoxy-2-pyridineboronic acid pinacol ester; 2-(5-Methoxypyridin-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Methoxypyridine-2-boronic acid neopentyl glycol ester (common alternative); 5-Methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-methoxypyridine; 5-Methoxy-2-pyridylboronic acid pinacol ester; PINACOL (5-METHOXYPYRIDIN-2-YL)BORONATE
EINECS	Contact for details

Quality Control

Our 5-Methoxypyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is available with every shipment and upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The product is light-sensitive and should be handled under an inert atmosphere for long-term storage to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Typical 98-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.