Description

5-Chloro-2-Ethynylbenzaldehyde is a versatile and highly functionalized aromatic aldehyde building block, distinguished by its reactive ethynyl and aldehyde groups. This compound is essential for advanced organic synthesis, enabling the construction of complex molecular architectures through reactions like Sonogashira coupling and aldehyde transformations. It is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for targeted therapies.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and plant growth regulators.
• Material Science Building Block: Employed in creating specialized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The ethynyl group serves as a critical handle for Sonogashira and other palladium-catalyzed coupling reactions.
• Ligand and Catalyst Development: Useful for constructing complex chelating ligands for catalytic systems.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D exploring new synthetic methodologies.

Basic Information

Product Name	5-Chloro-2-Ethynylbenzaldehyde
CAS No.	1309565-97-6
Molecular Formula	C9H5ClO
Molecular Weight	164.59 g/mol
Synonyms	2-Ethynyl-5-chlorobenzaldehyde; 5-Chloro-2-ethynylbenzaldehyde; Benzaldehyde, 5-chloro-2-ethynyl-; 5-Chloro-2-ethynyl-benzaldehyde; 1309565-97-6; 5-Chloro-2-ethynyl-benzaldehyde
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Ethynylbenzaldehyde is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with your specifications. Our quality commitment supports applications in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.