Description

2,5-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-pyridine is a high-value organoboron building block, specifically a pyridine-substituted pinacol boronic ester. This compound is critical for enabling advanced synthetic transformations in modern organic chemistry, particularly in cross-coupling reactions. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing functionalized pyridine cores.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic ester coupling partner for the formation of carbon-carbon bonds with aryl or heteroaryl halides, a cornerstone reaction in medicinal chemistry.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific heterocyclic structures.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for catalysis and metal-organic frameworks (MOFs) due to its coordinating pyridine nitrogen and boronate functionality.
• Material Science Research: A precursor for organic electronic materials, such as those used in OLEDs and organic photovoltaics, where conjugated systems are essential.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological systems and diagnostic applications.

Basic Information

Product Name	2,5-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-pyridine
CAS No.	1309443-99-9
Molecular Formula	C13H20BNO2
Molecular Weight	233.12 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,5-dimethylpyridine; 2,5-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2,5-Dimethylpyridine-4-boronic acid pinacol ester; 4-(Pinacolatoboryl)-2,5-dimethylpyridine; 2,5-Dimethyl-4-pyridineboronic acid pinacol ester; 2,5-Lutidine-4-boronic acid pinacol ester; 1309443-99-9
EINECS	Contact for details

Quality Control

Our 2,5-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization including NMR (1H, 13C, 11B), HPLC, and GC analysis to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, it is recommended to keep the product under an inert atmosphere (e.g., nitrogen or argon) at temperatures between 2°C and 8°C to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.