Description

(2-Bromo-3-Methylphenyl)(Pyrrolidin-1-Yl)Methanone CAS NO 1309366-09-3 is a high-purity, specialized organic building block featuring a brominated aromatic ketone core functionalized with a pyrrolidine moiety. This compound is of significant value in modern synthetic chemistry, serving as a versatile intermediate for constructing complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical development teams engaged in medicinal chemistry, agrochemical research, and advanced material science.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization campaigns due to its modifiable bromo and carbonyl groups.
• Agrochemical Synthesis: Serves as a precursor in the development of new-generation herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Precursor: Utilized in the creation of organic electronic materials, such as charge-transport molecules or photoactive components.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific molecular scaffold.

Basic Information

Item	Detail
Product Name	(2-Bromo-3-Methylphenyl)(Pyrrolidin-1-Yl)Methanone
CAS No.	1309366-09-3
Molecular Formula	C12H14BrNO
Molecular Weight	268.15 g/mol
Synonyms	1-(2-Bromo-3-methylbenzoyl)pyrrolidine; N-(2-Bromo-3-methylbenzoyl)pyrrolidine; (2-Bromo-3-methylbenzoyl)pyrrolidine; Pyrrolidine, 1-[(2-bromo-3-methylphenyl)carbonyl]-; 1309366-09-3; AKOS026714192; 2-Bromo-3-methyl-N-pyrrolidinylbenzamide
EINECS	Contact for details

Quality Control

Our (2-Bromo-3-Methylphenyl)(Pyrrolidin-1-Yl)Methanone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.