Description

Ethyl 1-Methyl-4,5,6,7-Tetrahydro-1H-Pyrazolo[4,3-C]Pyridine-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial importance. This compound serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), enabling the development of next-generation therapeutics. It is primarily required by research institutions and pharmaceutical manufacturers engaged in drug discovery and process chemistry for central nervous system (CNS) and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of novel drug candidates, particularly those targeting neurological pathways.
• Drug Discovery & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in research laboratories.
• Active Pharmaceutical Ingredient (API) Synthesis: Integral to the multi-step synthesis of complex APIs, especially those containing fused pyrazolo-pyridine scaffolds.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical companies with custom synthesis and scale-up projects.
• Chemical Reference Standard: Serves as an analytical standard for quality control and method development in pharmaceutical analysis.
• Academic Research: Utilized in university and institutional research for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	Ethyl 1-Methyl-4,5,6,7-Tetrahydro-1H-Pyrazolo[4,3-C]Pyridine-3-Carboxylate
CAS No.	1309174-06-8
Molecular Formula	C12H17N3O2
Molecular Weight	235.28 g/mol
Synonyms	1-Methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxylic acid ethyl ester; Ethyl 1-methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxylate; 1H-Pyrazolo[4,3-c]pyridine-3-carboxylic acid, 4,5,6,7-tetrahydro-1-methyl-, ethyl ester; 1309174-06-8; Pyrazolo[4,3-c]pyridine derivative; Fused pyrazolopyridine intermediate.
EINECS	Contact for details

Quality Control

Our Ethyl 1-Methyl-4,5,6,7-Tetrahydro-1H-Pyrazolo[4,3-C]Pyridine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.