Description

2-(6-Fluoronaphthalen-2-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity, advanced pharmaceutical intermediate and a key building block in modern synthetic chemistry. This compound is specifically engineered for use in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures critical for drug discovery and materials science. It is an essential reagent for R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking reliable, high-quality boronic ester derivatives.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing fluorinated naphthalene scaffolds.
• Suzuki-Miyaura Cross-Coupling Reagent: Serves as a versatile organoboron partner for palladium-catalyzed carbon-carbon bond formation to create complex biaryl compounds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that leverage the fluorinated aromatic structure.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for the synthesis of fluorinated organic semiconductors and electron-transport materials.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Utilized in creating novel polymers and advanced organic materials with specific electronic or photophysical properties.

Basic Information

Product Name	2-(6-Fluoronaphthalen-2-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1308669-74-0
Molecular Formula	C16H20BFO2
Molecular Weight	274.14 g/mol
Synonyms	2-(6-Fluoro-2-naphthyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 6-Fluoro-2-naphthaleneboronic acid pinacol ester; 2-(6-Fluoronaphthalen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 6-Fluoro-2-naphthylboronic acid pinacol ester; Pinacol 6-Fluoro-2-naphthylboronate; (6-Fluoronaphthalen-2-yl)boronic acid pinacol ester; 1308669-74-0; 2-(6-Fluoro-naphthalen-2-yl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-(6-Fluoronaphthalen-2-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed specifications are provided and can be tailored to meet specific customer requirements for research or cGMP production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.