Description

3-Fluoro-3-Phenyloxetane is a high-value, fluorinated oxetane building block of significant interest in advanced organic synthesis. Its unique structure, featuring a fluorine atom on the oxetane ring, makes it a critical precursor for developing novel pharmaceuticals, agrochemicals, and functional materials. This compound is primarily sought after by research and development chemists in the pharmaceutical industry for creating complex molecules with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides where the introduction of fluorine improves biological activity and environmental persistence.
• Material Science: Serves as a monomer or cross-linking agent for synthesizing specialty polymers with tailored properties like chemical resistance, low surface energy, or specific optical characteristics.
• Ligand and Catalyst Development: Employed in the design of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Fluorine Chemistry Library Synthesis: A valuable building block for constructing diverse compound libraries in drug discovery for high-throughput screening.
• Academic and Industrial R&D: Used in fundamental research to study the reactivity of fluorinated heterocycles and ring-opening polymerization mechanisms.

Basic Information

Item	Detail
Product Name	3-Fluoro-3-Phenyloxetane
CAS No.	1305207-61-7
Molecular Formula	C9H9FO
Molecular Weight	152.17 g/mol
Synonyms	3-Fluoro-3-phenyloxetane; 3-Fluoro-3-phenyloxacyclobutane; 3-Phenyl-3-fluorooxetane; Oxetane, 3-fluoro-3-phenyl-; 1305207-61-7; 3-Fluoro-3-phenyl-oxetane; 3-Fluoro-3-phenyl-1-oxacyclobutane
EINECS	Contact for details

Quality Control

Our 3-Fluoro-3-Phenyloxetane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.