Description

2,2-Difluoroethyldifluoroacetate is a high-purity fluorinated building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals, agrochemicals, and specialty materials, where the introduction of fluorine atoms is critical for modulating biological activity and material properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries seeking to incorporate difluoroacetate motifs into novel molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring difluoroethyl or difluoroacetate functional groups to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where fluorine substitution can improve efficacy and environmental profile.
• Material Science Precursor: Acts as a monomer or modifying agent in the development of fluorinated polymers and specialty materials with unique surface properties, chemical resistance, or optical characteristics.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for introducing fluorinated segments into complex organic molecules via esterification or transesterification reactions.
• Liquid Crystal & Electronic Chemicals: Potential use in the synthesis of fluorinated components for liquid crystal displays (LCDs) and other electronic applications requiring specific dielectric properties.

Basic Information

Product Name	2,2-Difluoroethyldifluoroacetate
CAS No.	1300698-74-1
Molecular Formula	C4H4F4O2
Molecular Weight	160.07 g/mol
Synonyms	Difluoroacetic acid 2,2-difluoroethyl ester; 2,2-Difluoroethyl 2,2-difluoroacetate; Ethanol, 2,2-difluoro-, 2,2-difluoroacetate; 2,2,2',2'-Tetrafluoroethyl acetate; DFEA
EINECS	Contact for details

Quality Control

Our 2,2-Difluoroethyldifluoroacetate is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and consistency, meeting the exacting standards required for research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area. Recommended storage temperature is 2-8°C for long-term stability. The material is moisture-sensitive; keep container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.