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2,3-Dimethyl-2H-Indazole-6-Boronic Acid Pinacol Ester CAS NO 1300582-62-0


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CAS No.:1300582-62-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2,3-Dimethyl-2H-Indazole-6-Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and building block for organic synthesis. This compound is valued for its role as a protected boronic acid derivative, offering enhanced stability and handling properties for critical cross-coupling reactions. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

  • Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of complex organic molecules, particularly in medicinal chemistry.
  • Pharmaceutical Intermediate: Serves as a crucial building block in the research and development of new active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
  • Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific heterocyclic frameworks.
  • Material Science Research: Employed in the synthesis of organic electronic materials, such as OLEDs and organic semiconductors, where precise molecular structure is critical.
  • Chemical Biology & Probe Development: Utilized for creating molecular probes and labeled compounds for biological target identification and validation.
  • Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name 2,3-Dimethyl-2H-Indazole-6-Boronic Acid Pinacol Ester
CAS No. 1300582-62-0
Molecular Formula C15H21BN2O2
Molecular Weight 272.15 g/mol
Synonyms 2,3-Dimethyl-2H-indazol-6-ylboronic acid pinacol ester; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dimethyl-2H-indazole; 2,3-Dimethyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-indazole; 2H-Indazole-6-boronic acid, 2,3-dimethyl-, pinacol ester; 2,3-Dimethylindazole-6-boronic acid pinacol ester; Pinacol 2,3-dimethyl-2H-indazole-6-boronate
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Quality Control

Our 2,3-Dimethyl-2H-Indazole-6-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal stability. Keep away from incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (HPLC) Conforms to reference standard
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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