Description

1,3-Dimethyl-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indazole CAS NO 1300582-61-9 is a high-value, functionalized indazole derivative featuring a pinacol boronate ester group. This compound serves as a critical synthetic intermediate, enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions. It is primarily utilized by pharmaceutical research and development organizations, agrochemical innovators, and advanced material scientists for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Enables the creation of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, through precise molecular engineering.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of molecular probes and inhibitors for target identification and validation.
• Academic & Contract Research: Essential reagent for methodological development in organic synthesis and catalysis research within university and CRO laboratories.

Basic Information

Product Name	1,3-Dimethyl-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indazole
CAS No.	1300582-61-9
Molecular Formula	C15H21BN2O2
Molecular Weight	272.15 g/mol
Synonyms	6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-dimethyl-1H-indazole; 1,3-Dimethyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole; 1,3-Dimethyl-1H-indazole-6-boronic acid pinacol ester; 1,3-Dimethyl-6-(pinacolboryl)-1H-indazole; 6-(Pinacolatoboryl)-1,3-dimethyl-1H-indazole; 1,3-Dimethylindazole-6-boronic acid pinacol ester; 1,3-Dimethyl-6-boronic acid pinacol ester indazole
EINECS	Contact for details

Quality Control

Our 1,3-Dimethyl-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. For long-term storage, it is recommended to keep the material under an inert atmosphere (e.g., nitrogen or argon) at temperatures between 2°C and 8°C to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.