Description

2H-1-Benzopyran-3-Carboxaldehyde, 2,2-Dimethyl-7-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]- is a high-purity, advanced pharmaceutical intermediate characterized by its complex benzopyran core structure. This compound is of significant commercial importance for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders or inflammatory pathways.
• Medicinal Chemistry Research: Used by R&D laboratories for structure-activity relationship (SAR) studies and lead optimization programs to develop new chemical entities.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for the production of clinical trial materials and commercial APIs.
• Academic Research: Utilized in university and institutional research for exploring new organic synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	2H-1-Benzopyran-3-Carboxaldehyde, 2,2-Dimethyl-7-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]-
CAS No.	1298093-47-6
Molecular Formula	C₁₇H₂₂O₄
Molecular Weight	290.35 g/mol
Synonyms	2,2-Dimethyl-7-[(tetrahydro-2H-pyran-2-yl)oxy]-2H-1-benzopyran-3-carboxaldehyde; 7-(Tetrahydro-2H-pyran-2-yloxy)-2,2-dimethyl-2H-chromene-3-carbaldehyde; THP-protected Chromene-3-carboxaldehyde; 2,2-Dimethyl-7-(tetrahydropyran-2-yloxy)chromene-3-carbaldehyde; Advanced Benzopyran Intermediate; Chromene Derivative THP Ether
EINECS	Contact for details

Quality Control

Our 2H-1-Benzopyran-3-Carboxaldehyde, 2,2-Dimethyl-7-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.