Description

Brettphos Auntf2 CAS NO 1296269-97-0 is a specialized organophosphorus ligand, specifically a dialkylbiarylphosphine, designed for high-performance cross-coupling catalysis. This compound matters because it enables efficient and selective palladium-catalyzed reactions, which are critical for constructing complex molecules in advanced chemical synthesis. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for applications such as Buchwald-Hartwig amination and Suzuki-Miyaura coupling.

Application

• As a premier ligand for Buchwald-Hartwig C-N and C-O cross-coupling reactions in pharmaceutical intermediate synthesis.
• Enabling high-yield Suzuki-Miyaura C-C bond formation for constructing biaryl structures in agrochemicals.
• Facilitating challenging cross-couplings with sterically hindered substrates in academic and industrial R&D.
• Use in the development of novel organic electronic materials and functional polymers.
• Catalytic applications in process chemistry for scale-up and manufacturing of active pharmaceutical ingredients (APIs).
• As a key component in pre-formed palladium catalyst systems for enhanced reactivity and stability.

Basic Information

Item	Detail
Product Name	Brettphos Auntf2
CAS No.	1296269-97-0
Molecular Formula	C₃₁H₄₀NO₃P
Molecular Weight	505.62 g/mol
Synonyms	BrettPhos AUNTf2; 2-(Dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl Trifluoromethanesulfonamide; 2-(Dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-triisopropylbiphenyl Triflamide; t-BuBrettPhos Triflamide; AUNTf2-BrettPhos; BrettPhos trifluoromethanesulfonamide; Dialkylbiarylphosphine ligand AUNTf2
EINECS	Contact for details

Quality Control

Our Brettphos Auntf2 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and NMR for structural confirmation, to ensure it meets the high standards required for sensitive catalytic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain optimal purity and performance. Keep the container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.