Description

Ethyl 3,3-Difluoro-2-Oxopent-4-Enoate is a high-value fluorinated building block and synthon used in advanced organic synthesis. This compound is critical for introducing difluoroalkyl and keto-ester functionalities into target molecules, enabling the development of novel chemical entities with modified properties. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring difluoromethyl or fluorinated ketone motifs to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the introduction of fluorine atoms can improve activity and environmental profile.
• Material Science Research: Employed as a monomer or cross-linking agent in the development of specialty polymers and advanced materials with unique surface properties.
• Fluorine Chemistry & Catalysis: Acts as a substrate in methodological studies for developing new fluorination reactions and catalytic processes.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up campaigns in fine chemical production.

Basic Information

Product Name	Ethyl 3,3-Difluoro-2-Oxopent-4-Enoate
CAS No.	1294512-26-7
Molecular Formula	C7H8F2O3
Molecular Weight	178.13 g/mol
Synonyms	Ethyl 3,3-difluoro-2-oxopent-4-enoate; 4-Pentenoic acid, 3,3-difluoro-2-oxo-, ethyl ester; 3,3-Difluoro-2-oxo-4-pentenoic acid ethyl ester; Ethyl 3,3-difluoro-2-oxopent-4-enoate; Difluoro Oxo Pentenoate Ester
EINECS	Contact for details

Quality Control

Our Ethyl 3,3-Difluoro-2-Oxopent-4-Enoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP, ISO, and REACH standards for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.