Description

3-(Chloromethyl)-1,1-Difluorocyclobutane is a high-value, multi-functional organofluorine building block. This compound is strategically important for introducing the cyclobutyl and difluoromethylene motifs into advanced molecular architectures. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorine-containing components in electronic display materials, enhancing stability and performance.
• Polymer & Material Science: Employed as a monomer or cross-linking agent to create specialty polymers with unique thermal and chemical resistance properties.
• Organic Synthesis Reagent: A versatile reagent for introducing the 1,1-difluorocyclobutane scaffold, a valuable isostere in medicinal chemistry.
• Fluorine Chemistry Research: Essential for academic and industrial research exploring new fluorination methodologies and the properties of fluorinated cyclobutanes.

Basic Information

Product Name	3-(Chloromethyl)-1,1-Difluorocyclobutane
CAS No.	1290625-58-9
Molecular Formula	C5H7ClF2
Molecular Weight	140.56 g/mol
Synonyms	1,1-Difluoro-3-(chloromethyl)cyclobutane; (Chloromethyl)-1,1-difluorocyclobutane; 3-Chloromethyl-1,1-difluorocyclobutane; 1,1-Difluoro-3-chloromethylcyclobutane; Cyclobutane, 1,1-difluoro-3-(chloromethyl)-; 1290625-58-9
EINECS	Contact for details

Quality Control

Our 3-(Chloromethyl)-1,1-Difluorocyclobutane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.