Description

3-(Phenylmethyl)-2-[(1E)-2-(3-Pyridinyl)Ethenyl]-4(3H)-Quinazolinone is a specialized heterocyclic organic compound of significant interest in advanced pharmaceutical research and development. This molecule serves as a critical synthetic intermediate or a potential pharmacophore for designing novel therapeutic agents. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry and drug discovery programs. The compound's unique quinazolinone-pyridine hybrid structure offers a versatile scaffold for probing biological activity.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and high-throughput screening libraries.
• Kinase Inhibitor Development: Potential precursor for compounds designed to modulate kinase activity, relevant in oncology and inflammatory diseases.
• Biochemical Tool Compound: Serves as a probe in biochemical assays to study enzyme function and cellular signaling mechanisms.
• Organic Synthesis Reference Standard: Used as a pure reference material for analytical method development and validation in R&D laboratories.

Basic Information

Product Name	3-(Phenylmethyl)-2-[(1E)-2-(3-Pyridinyl)Ethenyl]-4(3H)-Quinazolinone
CAS No.	1290541-46-6
Molecular Formula	C22H17N3O
Molecular Weight	339.39 g/mol
Synonyms	2-[(E)-2-(Pyridin-3-yl)vinyl]-3-benzylquinazolin-4(3H)-one; 3-Benzyl-2-[(E)-2-(pyridin-3-yl)vinyl]quinazolin-4(3H)-one; 3-Benzyl-2-[(E)-2-(3-pyridyl)vinyl]-4(3H)-quinazolinone; 2-[(1E)-2-(3-Pyridinyl)ethenyl]-3-(phenylmethyl)-4(3H)-quinazolinone; 1290541-46-6; Quinazolinone derivative, 3-benzyl-2-styryl-
EINECS	Contact for details

Quality Control

Our 3-(Phenylmethyl)-2-[(1E)-2-(3-Pyridinyl)Ethenyl]-4(3H)-Quinazolinone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research specifications. Our quality commitment supports applications requiring high-purity reference standards and intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.