Description

4-Bromo-2-Hydroxynicotinaldehyde is a versatile and highly functionalized pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine, hydroxyl, and aldehyde substituents, makes it an invaluable precursor for constructing complex heterocyclic systems and pharmaceutical intermediates. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Building block for developing new pesticides, herbicides, and plant growth regulators with enhanced activity.
• Ligand and Catalyst Development: Used to create complex chelating ligands for metal catalysis and coordination chemistry applications.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced polymers and organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Academic & Contract Research: Fundamental reagent for methodological development and exploratory synthesis in university and CRO laboratories.

Basic Information

Product Name	4-Bromo-2-Hydroxynicotinaldehyde
CAS No.	1289196-72-0
Molecular Formula	C6H4BrNO2
Molecular Weight	202.01 g/mol
Synonyms	4-Bromo-2-hydroxypyridine-3-carbaldehyde; 2-Hydroxy-4-bromonicotinaldehyde; 3-Formyl-4-bromo-2-hydroxypyridine; 4-Bromo-2-oxo-1,2-dihydropyridine-3-carbaldehyde; 4-Bromo-2-pyridone-3-carboxaldehyde; 1289196-72-0; 4-Bromo-2-hydroxynicotinaldehyde
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2-Hydroxynicotinaldehyde is manufactured and tested under strict quality management protocols to ensure consistency and purity for research and development applications. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.