Description

6-Hydroxy-5-Methylnicotinaldehyde is a versatile and high-value pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both aldehyde and hydroxyl functional groups on the pyridine ring, makes it an essential precursor for creating complex heterocyclic compounds. This intermediate is particularly valuable for pharmaceutical R&D, agrochemical development, and the synthesis of specialty fine chemicals, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Building block for developing advanced pesticides, herbicides, and plant growth regulators with specific activity.
• Ligand and Catalyst Development: Used to create complex chelating ligands for metal catalysts in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Intermediate for synthesizing functionalized polymers, organic semiconductors, and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and other specialty chemicals requiring a substituted nicotinaldehyde core.

Basic Information

Product Name	6-Hydroxy-5-Methylnicotinaldehyde
CAS No.	1289194-02-0
Molecular Formula	C7H7NO2
Molecular Weight	137.14 g/mol
Synonyms	5-Methyl-6-hydroxynicotinaldehyde; 5-Methyl-6-oxo-1,6-dihydropyridine-3-carbaldehyde; 3-Formyl-5-methylpyridin-2(1H)-one; 6-Hydroxy-5-methyl-3-pyridinecarboxaldehyde; 5-Methyl-2-oxo-1,2-dihydropyridine-3-carbaldehyde; 6-Hydroxy-5-methylnicotinic aldehyde
EINECS	Contact for details

Quality Control

Our 6-Hydroxy-5-Methylnicotinaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment to ensure consistency and compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.