Description

3-Amino-5-Bromopicolinaldehyde is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique structure, featuring both an aldehyde and an amino group on a brominated pyridine core, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, leveraging its halogenated pyridine scaffold.
• Ligand and Catalyst Development: Serves as a versatile starting material for creating chelating ligands and organocatalysts in asymmetric synthesis.
• Material Science Research: Employed in the construction of organic semiconductors, metal-organic frameworks (MOFs), and other functional organic materials.
• Chemical Biology Probes: Utilized to develop fluorescent tags and molecular probes for studying biological processes.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions.

Basic Information

Product Name	3-Amino-5-Bromopicolinaldehyde
CAS No.	1289168-19-9
Molecular Formula	C6H5BrN2O
Molecular Weight	201.02 g/mol
Synonyms	5-Bromo-3-aminopicolinaldehyde; 5-Bromo-3-aminopyridine-2-carboxaldehyde; 2-Pyridinecarboxaldehyde, 5-bromo-3-amino-; 3-Amino-5-bromo-2-pyridinecarboxaldehyde; 5-Bromo-3-amino-2-formylpyridine; 3-Amino-5-bromopyridine-2-carbaldehyde; 5-Bromo-3-aminopyridine-2-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 3-Amino-5-Bromopicolinaldehyde is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliable supply for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.