Description

2-Amino-4-Bromonicotinaldehyde is a versatile brominated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both an aldehyde and an amino group on the pyridine core, makes it an indispensable precursor for constructing complex heterocyclic scaffolds. This high-purity intermediate is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Building block for the preparation of organic semiconductors, light-emitting materials, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and fluorescent tags for biochemical and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: A high-value intermediate for custom synthesis projects and scale-up manufacturing under cGMP conditions.

Basic Information

Product Name	2-Amino-4-Bromonicotinaldehyde
CAS No.	1289139-45-2
Molecular Formula	C6H5BrN2O
Molecular Weight	201.02 g/mol
Synonyms	4-Bromo-2-aminonicotinaldehyde; 2-Amino-4-bromopyridine-5-carboxaldehyde; 5-Bromo-6-aminonicotinaldehyde; 4-Bromo-2-aminopyridine-5-carbaldehyde; 2-Amino-4-bromo-5-formylpyridine; 5-Formyl-4-bromo-2-aminopyridine; 4-Bromo-2-amino-5-pyridinecarboxaldehyde; 2-Amino-4-bromo-3-pyridinecarboxaldehyde (isomer)
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Bromonicotinaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production facilities adhere to ISO standards, and we support our clients' regulatory needs for pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.