Description

4-Bromo-3-Methoxypicolinaldehyde is a versatile and high-value brominated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both an aldehyde and a bromine substituent on the methoxypyridine ring, makes it an indispensable precursor for constructing complex heterocyclic frameworks. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs or molecular sensors.
• Chemical Biology Probes: Utilized to create tagged molecules or probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Bromo-3-Methoxypicolinaldehyde
CAS No.	1289070-32-1
Molecular Formula	C7H6BrNO2
Molecular Weight	216.03 g/mol
Synonyms	4-Bromo-3-methoxypyridine-2-carboxaldehyde; 2-Formyl-4-bromo-3-methoxypyridine; 4-Bromo-3-methoxy-2-pyridinecarboxaldehyde; 3-Methoxy-4-bromopicolinaldehyde; 4-Bromo-3-methoxypicolinaldehyde; 2-Pyridinecarboxaldehyde, 4-bromo-3-methoxy-; 4-Bromo-3-methoxy-2-formylpyridine
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Methoxypicolinaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and propensity to be easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.