Description

3-Amino-2-Chloroisonicotinaldehyde is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of reactive aldehyde, amino, and chloro substituents on the pyridine ring, enabling diverse derivatization pathways. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a critical precursor for developing novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides with targeted modes of action.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and R&D: A versatile starting material for contract research organizations and fine chemical companies engaged in custom synthesis projects.

Basic Information

Product Name	3-Amino-2-Chloroisonicotinaldehyde
CAS No.	1289046-28-1
Molecular Formula	C6H5ClN2O
Molecular Weight	156.57 g/mol
Synonyms	2-Chloro-3-aminoisonicotinaldehyde; 2-Chloro-3-aminopyridine-4-carboxaldehyde; 4-Pyridinecarboxaldehyde, 3-amino-2-chloro-; 3-Amino-2-chloro-4-formylpyridine; 2-Chloro-3-aminopyridine-4-carbaldehyde; 3-Amino-2-chloroisonicotinic aldehyde
EINECS	Contact for details

Quality Control

Our 3-Amino-2-Chloroisonicotinaldehyde is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements of research and production applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C to minimize oxidation and degradation. Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.