Description

3-Bromo-4-Chloropicolinaldehyde is a high-purity halogenated picolinaldehyde derivative, serving as a critical building block in advanced organic synthesis. Its unique bifunctional structure, featuring both an aldehyde group and halogen substituents on the pyridine ring, makes it an indispensable precursor for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated pyridine core.
• Ligand Synthesis: Serves as a precursor for creating sophisticated chelating ligands used in catalysis and material science.
• Functional Material Development: Employed in the research of organic electronic materials, such as OLEDs and semiconductors.
• Cross-Coupling Reactions: The bromo and chloro groups provide orthogonal reactivity for sequential palladium-catalyzed cross-coupling reactions.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for biochemical and diagnostic applications.

Basic Information

Product Name	3-Bromo-4-Chloropicolinaldehyde
CAS No.	1289031-51-1
Molecular Formula	C6H3BrClNO
Molecular Weight	220.45 g/mol
Synonyms	4-Chloro-3-bromopicolinaldehyde; 3-Bromo-4-chloro-2-pyridinecarboxaldehyde; 2-Pyridinecarboxaldehyde, 3-bromo-4-chloro-; Picolinaldehyde, 3-bromo-4-chloro-; 3-Br-4-Cl-picolinaldehyde
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Chloropicolinaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications in cGMP environments and advanced research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.