Description

4-Amino-5-Bromonicotinaldehyde is a high-value, multi-functional heterocyclic building block with significant synthetic utility. Its molecular structure, featuring both an aldehyde and an amino group on a brominated pyridine ring, makes it a versatile precursor for constructing complex nitrogen-containing scaffolds. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries. It serves as a critical intermediate in the synthesis of active pharmaceutical ingredients (APIs), ligands for catalysis, and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly kinase inhibitors, antiviral agents, and other nitrogen-rich heterocyclic compounds.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and fungicides that require specific pyridine-based architectures.
• Ligand and Catalyst Development: The amino and aldehyde functionalities allow for the creation of complex chelating ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new organic reactions and synthesizing libraries of compounds for screening.
• Material Science Precursor: Potential use in the synthesis of organic semiconductors, dyes, and photoactive materials due to its conjugated system.

Basic Information

Product Name	4-Amino-5-Bromonicotinaldehyde
CAS No.	1289001-34-8
Molecular Formula	C6H5BrN2O
Molecular Weight	201.02 g/mol
Synonyms	5-Bromo-4-aminonicotinaldehyde; 3-Pyridinecarboxaldehyde, 4-amino-5-bromo-; 4-Amino-5-bromo-3-pyridinecarboxaldehyde; 5-Bromo-4-aminopyridine-3-carbaldehyde; 4-Amino-5-bromopyridine-3-carboxaldehyde; 5-Bromo-4-amino-3-formylpyridine; 3-Formyl-5-bromo-4-aminopyridine
EINECS	Contact for details

Quality Control

Our 4-Amino-5-Bromonicotinaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (by HPLC), identity confirmation (by IR and NMR), and levels of specific impurities. Our quality management system supports compliance with relevant standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized and light-sensitive. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Impurity (HPLC)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.