Description

[4-Chloro-2-(3,5-Dimethyl-1H-Pyrazol-1-Yl)Phenyl]Boronic Acid is a high-value, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-purity intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, enabling the creation of complex bioactive molecules.
• Material Science Research: Employed in the development of organic electronic materials, such as polymers for OLEDs and organic photovoltaics, due to its ability to form conjugated systems.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the creation of molecular probes and sensors that leverage boronic acid's affinity for diols, useful in diagnostic applications.
• Scale-up Process Chemistry: A reliable coupling partner for the efficient, large-scale production of biaryl and heterobiaryl structures under mild conditions.

Basic Information

Product Name	[4-Chloro-2-(3,5-Dimethyl-1H-Pyrazol-1-Yl)Phenyl]Boronic Acid
CAS No.	1287753-38-1
Molecular Formula	C13H14BClN2O2
Molecular Weight	276.52 g/mol
Synonyms	(4-Chloro-2-(3,5-dimethyl-1H-pyrazol-1-yl)phenyl)boronic acid; 4-Chloro-2-(3,5-dimethylpyrazol-1-yl)phenylboronic acid; 2-(3,5-Dimethyl-1H-pyrazol-1-yl)-4-chlorophenylboronic acid; 1-(4-Chloro-2-boronophenyl)-3,5-dimethyl-1H-pyrazole; Boronic acid, B-[4-chloro-2-(3,5-dimethyl-1H-pyrazol-1-yl)phenyl]-; CAS 1287753-38-1; 4-Chloro-2-(3,5-dimethylpyrazolyl)phenylboronic acid
EINECS	Contact for details

Quality Control

Our [4-Chloro-2-(3,5-Dimethyl-1H-Pyrazol-1-Yl)Phenyl]Boronic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to meet the exacting standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.