Description

2-(4-Iodophenyl)-6-Methyl-1,3,6,2-Dioxazaborocane-4,8-Dione is a specialized organoboron heterocyclic compound with the CAS registry number 1287221-36-6. This chemical is a valuable synthetic intermediate and building block, prized for its unique boron-containing dioxazaborocane core coupled with a reactive iodophenyl substituent. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in boron neutron capture therapy (BNCT) agents and protease inhibitors.
• Organic Synthesis Reagent: Used in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions due to the presence of the iodine atom and the boronate ester functionality.
• Materials Science Research: Serves as a precursor for developing boron-doped organic electronic materials and polymers.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes for studying enzyme function and mechanism.
• Agrochemical Development: Intermediate in the research and development of new crop protection agents with novel modes of action.
• Academic & Industrial R&D: A critical reagent for methodological studies in organometallic chemistry and new catalytic system development.

Basic Information

Product Name	2-(4-Iodophenyl)-6-Methyl-1,3,6,2-Dioxazaborocane-4,8-Dione
CAS No.	1287221-36-6
Molecular Formula	C12H13BINO4
Molecular Weight	388.95 g/mol
Synonyms	6-Methyl-2-(4-iodophenyl)-1,3,6,2-dioxazaborocane-4,8-dione; 2-(p-Iodophenyl)-6-methyl-1,3,6,2-dioxazaborocane-4,8-dione; 4,8-Dioxa-6-methyl-1-aza-2-bora-6-bicyclo[3.3.0]octan-3-one, 2-(4-iodophenyl)-; Iodophenyl dioxazaborocane dione; Boron heterocycle iodophenyl derivative; Organoboron building block CAS 1287221-36-6
EINECS	Contact for details

Quality Control

Our 2-(4-Iodophenyl)-6-Methyl-1,3,6,2-Dioxazaborocane-4,8-Dione is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO 9001 standards for traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.