Description

5-Fluoro-1-Methyl-1H-Indazole-6-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its distinct indazole core structure with fluorine and aldehyde functional groups. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel, targeted therapeutic agents. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of small molecule drugs, particularly for oncology and central nervous system (CNS) applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) for investigational new drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel drug candidates.
• Kinase Inhibitor Development: Serves as a core scaffold for designing potent and selective kinase inhibitors, a major class in oncology therapeutics.
• Chemical Library Synthesis: Employed in combinatorial chemistry to create diverse compound libraries for high-throughput screening.
• Agrochemical Research: Potential use as an intermediate in the development of new crop protection agents.
• Material Science: Investigated as a monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	5-Fluoro-1-Methyl-1H-Indazole-6-Carbaldehyde
CAS No.	1286734-88-0
Molecular Formula	C9H7FN2O
Molecular Weight	178.16 g/mol
Synonyms	5-Fluoro-1-methyl-1H-indazole-6-carboxaldehyde; 6-Formyl-5-fluoro-1-methylindazole; 1-Methyl-5-fluoro-1H-indazole-6-carbaldehyde; 5-Fluoro-1-methylindazole-6-carbaldehyde; 1286734-88-0; 5-Fluoro-1-methyl-6-indazolecarboxaldehyde; 1-Methyl-5-fluoroindazole-6-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 5-Fluoro-1-Methyl-1H-Indazole-6-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles suitable for pharmaceutical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.